Process Containment

Rheo has managed the material handling requirements for many pharmaceutical operations. Our familiarity with the equipment used in these processes allows us to provide single use containment isolators around this equipment. Containing the dust at the source of generation is the first step in a proper containment strategy. Single use containment isolators can be a great option for containing dusty processes.

Mini-Roller Compactor

Containment of a mini-roller compactor is provided by a flexible enclosure surrounding the compactor head while leaving the related motors, controls, and other components outside of the enclosure. A portable stainless steel frame and containment attachment flange is provided for attachment of the flexibles. Sleeves and bag-in/bag-out (BIBO) kits are provided for moving product and supplies in and out of enclosure. RheoPacs and Continuous Liners can be included for contained charging and discharging product.

Lab Scale V-Blender

Containment of a lab scale v-blender is provided by a flexible enclosure surrounding the entire machine. A portable stainless steel frame with a containment pan is used to attach the flexible enclosure. Sleeves and bag-in/bag-out (BIBO) kits are provided for charging, collection of product, and moving product and supplies in and out of enclosure.

Tablet Coater

Containment for a tablet coater is provided by one or two separate flexible enclosures attached to stainless steel containment flanges. One enclosure contains the pan access door and the second (optional) the exhaust filter access door. Stainless steel frames are used to attach the enclosures and bag-in/bag-out (BIBO) kits. Each enclosure is designed to include necessary gloves and bag-in/bag-out (BIBO) sleeves for a fully contained operation of the tablet coater.

Fluid Bed Dryer Granulator

Containment of a Fluid Bed Dryer Granulator (Glatt GPGC2 for example) is provided by two enclosures that allow for access to the dryer granulator bowl and the filters. Two flanges are added to the equipment that allow for attachment of the flexible enclosures. Cantilevered frames support the enclosures while offloading the dried powder and changing the filters. RheoCrimp technology is used for containment of the powders through a bag-in/bag-out BIBO kit and used filters during separation. The frame can be designed to be retracted and collapsed for storage.

Automated RheoPac Filling

This system offers an automated or semi-automated filling of RheoPacs using a Rheo Drum Inverter and disposable funnel liner to transfer powder from drums into a range of RheoPac sizes. The optional 4 bag carousel cart allows for easy rotation and filling of the bags with an integrated transport cart for moving the RheoPacs into the process area.

RheoPac Dispensing

The Rheo Column Lift can be used to lift the RheoPac carousel off of the transport cart and into position above the receiving vessel. The carousel design allows the operator to rotate from RheoPac to RheoPac to quickly unload multiple bags with a single lifting and positioning operation. Our automation control systems ensures reliable and accurate position of the carousel system to reduce operator time in the handling process.

Weigh & Dispense System

This Material Transfer Station is designed to help operators transfer material out of drums using a small footprint workstation that incorporates a Drum Tipper and Ventilation Sleeve for minimal dust during weigh and dispense operations. An integrated weighing module holds the RheoPac on a frame that is isolated from the workstation and sits on load cells to provide excellent weighing accuracy.

Dust Collector Enclosure

Flexible enclosure to house a small dust collector. The enclosure is used to remove the dust collected for accountability purposes, all while maintaining containment. Filters can be disposed using the bag-in/bag-out (BIBO) sleeves.

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Tablet Press

Containment for a tablet press is provided by a combination of several separate flexible enclosures attached to stainless steel containment flanges and pans. Portable stainless steel attachment frames are provided for each of the flexible enclosures. One enclosure contains the press while the others contain tablet testing, metal checking, and tablet discharge. Each enclosure is designed to include necessary gloves, bag-in/bag-out (BIBO) kits, and continuous liners for a fully contained operation of the tablet press.

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Cone Mill

Containment of a cone mill is provided by a flexible enclosure surrounding the mill head and inlet hopper while leaving the related motors, controls, and other components outside of the enclosure. Sleeves and bag-in/bag-out (BIBO) kits are provided for charging, collection of product, and moving product and supplies in and out of enclosure.

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Pill Testing

This enclosure is used to contain the equipment used in testing sample pills in process development from a tablet press. The flexible enclosure features a zipper to set the equipment inside and a bag-in/bag-out (BIBO) port to bring items in and out of the enclosure in a contained manner.

Benchtop Weighing Isolator

This flexible enclosure can house a small scale to subdivide API into smaller containers. Bag-in/bag-out (BIBO) ports are used to bring items in and out. A spray wand can be used to wet surfaces after use. The gas tight zipper helps to set up items before the API container is opened.